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Medication that inhibit CYP2D6 activity, such as paroxetine and quinidine, may cause diminished clearance of oxycodone which could lead on to an increase in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by eleven%, AUC by thirteen%, and t½ elim.Breastfeeding Administration to nursing G

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